The Avian Polyoma Virus is one of the most significant viral pathogens in parrots that causes substantial economic losses for aviculturists. Signs and symptoms of APV are very similar to and often confused with PBFD. With a high mortality rate, acute APV causes sudden death in chicks younger than 8-12 weeks and can kill chicks in the breeding season. With very little options available for treatment, prevention is the only method to protect the aviary from Avian Polyoma Virus.